It is often prescribed for individuals with pernicious anemia or other conditions that impair B absorption (for example, after gastric surgery or in certain digestive disorders)
If you experience side effects, your doctor might change how you get the shots or where you get them
When taking B12 via injections or high doses of supplements, it bypasses the absorption limits of dietary B12, leading to a temporary rise in blood B12 levels
The primary mechanisms of action include: Enhancing glucose-dependent insulin secretion from pancreatic beta cells, which helps lower blood glucose levels when they are elevated Suppressing glucagon release from pancreatic alpha cells, reducing hepatic glucose production [1] [2] Slowing gastric emptying , which moderates the rate at which nutrients enter the bloodstream Promoting satiety through central nervous system pathways, leading to reduced caloric intake [1] [2] These medications are peptide-based (and one fusion protein) and are temperature sensitive
Insufficient levels can lead to nerve damage, contributing to symptoms such as numbness, tingling, and cognitive decline
